The National Emerging Infectious Diseases Laboratories (NEIDL) at Boston University & Signify have conducted research that validates the effectiveness of 275nm UV-C light sources on the inactivation of SARS-CoV-2, the virus that causes COVID-19.
Dr. Anthony Griffiths, Associate Professor of Microbiology at Boston University School of Medicine and his team have been working on developing tools to support scientific advancement in this field. They have treated inoculated material with different doses of UV-C radiation coming from a UVC light source and assessed the inactivation capacity under various conditions. Test results show that the virus could no longer be detected after seconds of exposure.
A dose of 5mJ/cm2, resulted in a reduction of the SARS-CoV-2 virus of 99% in 6 seconds.
Based on the data, a dose of 22mJ/cm2 will result in a reduction of 99.9999% in 25 seconds.
👆Above should put to rest any suspicion on UVC efficacy on Covid19 in the Indian context, says Dr Kamal Sethia President ISLE.
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Novel LED irradiation system developed by the Ferdinand-Braun-Institut aims to kill microorganisms with ultra-short wave UV light – without side effects Within the framework of their Joint Lab GaN Optoelectronics, the Ferdinand-Braun-Institut (FBH) and Technische Universitat Berlin (TUB) have developed AlGaN LEDs emitting in the far UV spectral range. The LEDs emit at wavelengths around 230 nm and provide more than one milliwatt output power.
Unlike long-wave UVC radiation emitted by mercury vapour lamps, the 230nm UV light does not penetrate into the living layers of the skin. So it is hoped that it can be used either without any harm or minimal damage that will be repaired naturally. FBH has developed and produced an irradiation system comprising an array of 118 of these LEDs on an area of 8 cm x 8 cm. It achieves a maximum irradiation power of 0.2 mW/cm2 with more than 90 percent uniformity over an area of 6 cm x 6 cm.
The prototypes are delivered to the Department of Dermatology at Charite - Universitatsmedizin Berlin for skin examinations & the Institute for Hygiene and Environmental Medicine of the University Medicine Centre Greifswald to clarify the microbicidal effectiveness.
Prototypes aimed to validate procedures
Tests carried out by the two project partners with these devices are intended to show that UVC irradiation is suitable for killing microorganisms and especially MDR pathogens (eradication). At the same time, it is to be demonstrated that this exposure is harmless to human skin & nasal surface. as long as specific irradiation doses are maintained. the Charite conducts dose-dependent investigations of possible DNA damage to irradiated skin.
The University Medicine Centre Greifswald will determine how effectively the UV LED emitters kill MDR pathogens at 230 nm and compare the results with those of UV lamps with emission at 254 nm and 222 nm.
Miniaturisation and further applications
LEDs have many advantages and open up further perspectives: they are particularly small and thus permit miniaturised irradiation systems. These could be used endoscopically in body orifices or as hand-held devices. LEDs also emit only little heat and hardly put any strain on the skin. In addition, they do not require high voltage - an important safety aspect, The pathogens can be eliminated in places that are difficult to access.
The device might also be interesting for corona viruses, as they can also be inactivated by short-wave UVC light. Since SARS-CoV-2 replicates in the pharynx in the first phase, it seems plausible to use such light sources in this part of the body to prevent a COVID-19 disease
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